Do you feel tired often? Are you having trouble adding on muscle mass or even maintaining it?
If so, it might be a sign that you are low in Testosterone. Testosterone is a hormone produced
by both men and women. It is essential in the development of male growth and characteristics.
For women, the hormone is produced and necessary in smaller amounts. Some of the key roles
played by Testosterone are:
1. Production of Muscle Mass and Bones
2. Healthy Heart and Blood
3. Burning Body Fat
4. Improved Brain Function
5. Promotes Healthy Skin
Production of Muscle Mass
Testosterone is crucial for building muscle mass. It increases the number of available androgen
receptors that Testosterone can bind to within muscle. When this attachment occurs, protein
synthesis is activated and muscles begin to recover and grow. Another way that Testosterone is
crucial for muscle mass is that it is anti-catabolic.It blocks the ability of catabolic hormones, like
Cortisol, to attach to their primary receptors. Testosterone is fundamental for building and
maintaining muscle mass.(1)
Healthy Heart and Blood
Testosterone also plays a role in maintaining a healthy heart and healthy blood. Testosterone
increases EPO, Erythropoietin, which activates red blood cell development. When more red
blood cells are introduced to the body, more oxygen is also able to reach muscle cells. The US
National Library of Medicine also includes a study titled “Testosterone and the Heart” in which
participants increased Testosterone to aid various heart related conditions like Coronary Artery
Disease(2) and Congestive Heart Failure.(3)
Burning Body Fat
For both sexes, Testosterone works directly within the central nervous system (brain and spinal
cord) to regulate metabolism. Testosterone also blocks the uptake of fat and storage of fat. It
does this by increasing the amount of beta-adrenergic receptors, which burn body fat.(4)
Improves Brain Function
Testosterone has been shown to improve cognition, memory, and emotions.And when
Testosterone levels decline, the brain begins to suffer. In a study with aging men with or without
a brain impairment were given Testosterone, it showed a relation between decreasing
Testosterone and age-related cognitive diseases may exist.(5) Studies also show that
increasing Testosterone works to activate a cortical network, improving spatial cognition and
verbal and visual memory.(6)
Promotes Healthy Skin
The Testosterone/Estrogen ratio plays a huge part in the thickness and texture of skin. Because
men generally have more Testosterone, the skin is more dense and vigorous.(7) Testosterone
also supports collagen production which is the primary protein in skin. Maintaining a healthy
amount of collagen is crucial for skin elasticity as you age. On top of that, collagen protects
organs, provides structure to joints and tendons, and holds together bones and muscles.
(1)Kraemer, W. J., & Rogol, A. D. (Eds.). (2008). The Encyclopaedia of Sports Medicine: An IOC Medical
Commission Publication, The Endocrine System in Sports and Exercise (Vol. 11) . John Wiley & Sons
(2)Webb CM, Adamson DL, de Zeigler D, Collins P. Effect of acute testosterone on myocardial ischemia in men with
coronary artery disease. Am J Cardiol. 1999. February 1; 83 3: 437– 9, A9. [PubMed]
(3)Dos Santos MR, Sayegh AL, Bacurau AV, et al. Effect of Exercise Training and Testosterone Replacement on
Skeletal Muscle Wasting in Patients With Heart Failure With Testosterone Deficiency. Mayo Clin Proc. 2016. May; 91
5: 575– 86.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512682/
(5)Cogn Behav Neurol. 2016 Sep;29(3):122-38. doi: 10.1097/WNN.0000000000000104.
Effects of Testosterone Therapy on Cognitive Function in Aging: A Systematic Review.
Hua JT 1 , Hildreth KL, Pelak VS.
(6)Aging Male. 2006 Dec;9(4):195-9. Testosterone and the brain. Zitzmann M 1 .
(7)Markova MS, Zeskand J, McEntee B, Rothstein J, Jimenez SA, et al. (2004)